Location: Home > Scientists
  Principal Investigators
Name:
 CHEN Jinfeng
Subject:
 Genomics
Tel/Fax:
 +86-10-64807260  / 
E-mail:
 chenjinfeng@ioz.ac.cn
Address:
 The State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
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Resume:

May 2019-Sep 2020 Staff Scientist, City of Hope National Medical Center

Jul 2017-May 2019 Assistant Project Scientist, University of California, Riverside

Jan 2013-Jul 2017 Postdoctoral Fellow, University of California, Riverside

Jul 2012-Jan 2013 Postdoctoral Fellow, Institute of Genetics and Developmental Biology of Chinese Academy of Sciences

Education:

Sep 2006-Jul 2012 Ph.D.in Genetics, Institute of Genetics and Developmental Biology of Chinese Academy of Sciences

Sep 2004-Jul 2006 M.S.in Molecular Biology, Northwest A&F University

Sep 2000-Jul 2004 B.S.in Biotechnology, Northwest A&F University

Research Interests:
Comparative genomics; Host-parasite interactions.

Awards and Honors:

Professional Activities:

Research Grants:

Selected Publications:
  1. Chen J*#, Liu Y*, Liu M*, Guo W*, Wang Y*, He Q*, Chen W, Liao Y, Zhang W, Gao Y, Dong K, Ren R, Yang T, Zhang L, Qi M, Li Z, Zhao M, Wang H, Wang J, Qiao Z, Li H, Jiang Y, Liu G, Song X, Deng Y, Li H, Yan F, Dong Y, Li Q, Li T, Yang W, Cui J, Wang H, Zhou Y, Zhang X, Jia G, Lu P, Zhi H, Tang S#, Diao X#. Pangenome analysis reveals genomic variations associated with domestication traits in broomcorn millet. Nature Genetics. 2023; 55:2243-2254.
  2. He Q*, Tang S*, Zhi H*, Chen J*, Zhang J, Liang H, Alam O, Li H, Zhang H, Xing L, Li X, Zhang W, Wang H, Shi J, Du H, Wu H, Wang L, Yang P, Xing L, Yan H, Song Z, Liu J, Wang H, Tian X, Qiao Z, Feng G, Guo R, Zhu W, Ren Y, Hao H, Li M, Zhang A, Guo E, Yan F, Li Q, Liu Y, Tian B, Zhao X, Jia R, Feng B, Zhang J, Wei J, Lai J, Jia G#, Purugganan M#, Diao X#. A graph-based genome and pangenome variation of the model plant Setaria. Nature Genetics 2023; 55:1232-1242.
  3. Sun Y, Liu Y, Shi J, Wang L, Liang C, Yang J, Chen J#, Chen M#. Biased mutations and gene losses underlying diploidization of the tetraploid broomcorn millet genome. Plant J. 2023; 113:787-801.
  4. Liu N*, Xu Z*, Li Q*, Cao Y, Yang D, Liu S, Wang X, Mi Y, Liu Y, Ding C, Liu Y, Li Y, Yuan Y, Gao G, Chen J#, Qian W#, Zhang X#. A lncRNA fine-tunes salicylic acid biosynthesis to balance plant immunity and growth. Cell Host & Microbe. 2022; 30:1124–38.
  5. Liu Y, Rao J, Mi Y, Chen L, Feng L, Li Q, Geng J, Yang X, Zhan X, Ren L#, Chen J#, Zhang X#. SARS-CoV-2 RNAs are processed into 22-nt vsRNAs in Vero cells. Front Immunol. 2022; 13:1008084.
  6. Griffiths, J.I.*, Chen, J.*, Cosgrove, P.A., O’Dea, A., Sharma, P., Ma, C., Trivedi, M., Kalinsky, K., Wisinski, K.B., O’Regan, R., Makhoul, I., Spring, L.M., Bardia, A., Adler, F.R., Cohen, A.L., Chang, J.T., Khan, Q.J. & Bild, A.H. Serial single-cell genomics reveals convergent subclonal evolution of resistance as patients with early-stage breast cancer progress on endocrine plus CDK4/6 therapy. Nature Cancer. 2021; 2:658-671
  7. Chen J*, Lu L*, Robb SMC, Collin M, Okumoto Y, Stajich JE, Wessler SR. Genomic diversity generated by a transposable element burst in a rice recombinant inbred population. Proc Natl Acad Sci U S A. 2020; 117:26288-26297.
  8. Chen J, Lu L, Benjamin J, Diaz S, Hancock CN, Stajich JE, et al. Tracking the origin of two genetic components associated with transposable element bursts in domesticated rice. Nature communications. 2019; 10:641.
  9. Liao Y, Zhang X, Li B, Liu T, Chen J, Bai Z, Wang M, Shi J, Walling JG, Wing RA, Jiang J, Chen M. Comparison of Oryza sativa and Oryza brachyantha Genomes Reveals Selection-Driven Gene Escape from the Centromeric Regions. Plant Cell. 2018; 30:1729-1744. 
  10. Ou S, Chen J, Jiang N. Assessing genome assembly quality using the LTR Assembly Index (LAI). Nucleic Acids Res. 2018; 46:e126.
  11. Lu L*, Chen J*, Robb SMC, Okumoto Y, Stajich JE, Wessler SR. Tracking the genome-wide outcomes of a transposable element burst over decades of amplification. Proc Natl Acad Sci U S A. 2017; 114:E10550–E9.
  12. Chen J*, Huang Q*, Gao D*, Wang J*, Lang Y*, Liu T, et al. Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying Oryza genome evolution. Nature communications. 2013; 4:1595.
  13. Lu F, Ammiraju JS, Sanyal A, Zhang S, Song R, Chen J, et al. Comparative sequence analysis of MONOCULM1-orthologous regions in 14 Oryza genomes. Proc Natl Acad Sci U S A. 2009; 106:2071-6.