National Resource Center

The National Stem Cell Resource Bank (formerly known as the Beijing Stem Cell Bank), established in 2007, is a national science and technology resource-sharing service platform approved by the Ministry of Science and Technology and the Ministry of Finance. It falls under the category of foundational support and infrastructure for national science and technology innovation bases and is affiliated with the Institute of Zoology, Chinese Academy of Sciences. Addressing the needs of scientific innovation, population health, and socioeconomic development, the National Stem Cell Resource Bank takes the lead in strategically storing stem cell resources, enhancing the effective integration of high-quality cell resources, and improving the efficiency of cell resource utilization. It is committed to providing cell resource-sharing services for scientific research and industrial translation.

By ensuring the compliance, proprietary rights, diversity, and standardized establishment of cell resources, the National Stem Cell Resource Bank has built a cell resource-sharing service platform that meets both public welfare and usability requirements. To guarantee the compliance and traceability of cell resources, the Bank has implemented rigorous resource compliance measures, established a comprehensive quality management system, and obtained accreditation for ISO 20387 biobanking and ISO 17025 calibration and testing laboratory accreditation from the China National Accreditation Service for Conformity Assessment (CNAS), receiving the first domestic biobank accreditation certificate. To promote the standardization of cell resources, the Bank has led the publication of the first international stem cell standard (ISO 24603), the first national standard for human-derived stem cells (GB/T 42466-2023), and the first consortium standard for stem cells (T/CSCB 0001-2020) in collaboration with field experts. Additionally, it has spearheaded the release of over 20 national and consortium standards and participated in drafting more than 40 others, advancing the pioneering construction of a domestic standard system for cell resources. Based on this robust system, the Bank has established nearly 3,100 cell lines from diverse sources and developmental potentials, totaling over 80,000 cell samples, and has applied for more than 60 patents related to cell resources, ensuring proprietary rights and diversity.

The National Stem Cell Resource Bank continuously optimizes the full lifecycle management of cell resources and has successfully built an integrated online-offline cell resource-sharing service platform. Through high-quality cell resource-sharing services, the Bank has effectively supported the advancement of several major scientific research projects in the stem cell field and provided solid cell resource guarantees for multiple research teams. Additionally, it has supported over ten stem cell clinical research projects registered with national regulatory authorities, five of which have received approval from the National Medical Products Administration for Phase I/II drug clinical trials.

Currently, the National Stem Cell Resource Bank has established a comprehensive quality management system to support basic research and applications of stem cells, advance the construction of standards related to stem cell  (strategic deployment), promote the establishment of the China Collaborative Innovation Platform for Stem Cells and Regenerative Medicine, drive the development of the International Stem Cell Bank Initiative and the International Stem Cell Bank Alliance, and continuously provide cell resource and technology-sharing services. It is committed to advancing high-quality development in the fields of life sciences and pharmaceutical health. Looking ahead, the National Stem Cell Resource Bank will continue to expand its strategic reserve of cell resources, enhance the quality of cell resources, and significantly improve resource service capabilities. Focused on the frontiers of science and technology and people's health, it will provide stronger support and guarantees for the field with diverse, high-quality, and rigorously standardized cell resources.

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