JIAO Jianwei

JIAO Jianwei

  • Subject： Neural stem Cell
  • Tel/Fax: +86-10-64806335  / 
  • Email： jwjiao@ioz.ac.cn
  • Address： Institute of Stem Cell and Regenerative, Chinese Academy of Siences, Yard A3, Datun Road, Chaoyang District, Beijing, 100101, P.R.China
  • More： Group of Neural Stem Cell and Neurogenesis      

Research Interests

Our laboratory focuses on studying what mechanisms and signaling pathways control stem cell proliferation and neurogenesis. Identification of neuron-specific genes or miRNAs from neural stem cells is the direction of this study. There are several research directions including what mechanisms involving neural stem cell proliferation and neurogenesis and how to convert fibroblasts to neurons.

Research Grants

National Key Basic Research (973) Program, the National Science Foundation, the Strategic Priority Research Program.

Selected Publications

  1. Li Y, Li Z, She Y, He Z, Wang C, Zhang Y, Li R, Jin L, Ji F, Du P, Dong J*, Jiao J*. Decoding the spatiotemporal development of human meninges. Cell. 2026 doi: 10.1016/j.cell.2026.04.040.
  2. Zheng W, Peng B, Chen Z, Huang K, Qi Y, Niu H, Shen H, Wu J, Jiao J*, Du P*. Continuous modeling of primate embryogenesis from totipotency to early organogenesis. Cell. 2026 doi: 10.1016/j.cell.2026.05.023.
  3. Zhang M, Wang Y, Yang R, Ji F, Li S, Li C, Zhao X, Li H, Jiao J*. Microglia prune developing cortical blood vessels through PD-1 signaling. Nat Neurosci. 2026 (accepted).
  4. Li Z, Li Y, He Z, Wang C, Zhang Y, Li R, Jin L, Jiao J, Ji F, Zhu B, Zhang J, Du P, Dong J*, Jiao J*. Decoding the spatiotemporal development of the blood-brain barrier in human cortex. Cell Stem Cell. 2026 33:853-871.
  5. Zou W, Lv Y, Zhang S, Li L, Sun L, Jiao J*. Lysosomal dynamics regulate mammalian cortical neurogenesis. Dev Cell. 2024 59:64-78 (Cover).
  6. Wang Y, Wang W, Su L, Ji F, Zhang M, Xie Y, Zhang T, Jiao J*. BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development. Dev Cell. 2024 59:108-124.
  7. Li Y, Li Z, Wang C, Yang M, He Z, Wang F, Zhang Y, Li R, Gong Y, Wang B, Fan B, Wang C, Chen L, Li H, Shi P, Wang N, Wei Z, Wang YL, Jin L*, Du P*, Dong J*, Jiao J*. Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain. Cell. 2023 186:5892-5909.
  8. Li Y, Li Z, Yang M, Wang F, Zhang Y, Li R, Li Q, Gong Y, Wang B, Fan B, Wang C, Chen L, Li H, Ong J, Teng Z, Jin L*, Wang YL*, Du P*, Jiao J*. Decoding the temporal and regional specification of microglia in the developing human brain. Cell Stem Cell. 2022 29:620-634.
  9. Liang Q, Su L, Zhang D, Jiao J*. CD93 negatively regulates astrogenesis in response to MMRN2 through the transcriptional repressor ZFP503 in the developing brain. Proc Natl Acad Sci USA. 2020 117:9413-9422.
  10. Li Z, Li Y, Jiao J*. Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci USA. 2019 116:24122-24132.