QU Jing
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Subject: Regenerative medicine
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Tel/Fax: +86-10-64807768 /
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Email: qujing@ioz.ac.cn
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Address: State Key Laboratory of Stem Cell and Reproductive Biology Institute of Zoology, CAS. Beichen West Road 1#, Chaoyang District, Beijing, China. 100101
Resume
PROFILE
Research focuses on the molecular circuits underlying aging, emphasizing epigenetic remodeling, metabolic and immune dysregulation, and stem-cell decline. Work aims to define causal cross-organ signaling pathways and identify molecular effectors responsive to behavioral, nutritional, and metabolic inputs, with the goal of developing mechanistically grounded interventions for aging and age-related diseases.
HIGHLIGHTS OF ACADEMIC LEADERSHIP & IMPACT
- Founding President, the Aging Genetics Elites of the Genetics Society of China
- Member of the Academy for Health & Lifespan Research (AHLR)
- Member of the Scientific Planning Committee of the International Society for Stem Cell Research (ISSCR)
- Expert reviewer for UK Research and Innovation (UKRI) projects
- Executive Editor of Aging Medicine
- Editorial Board member for PLoS Biology, Cell Proliferation, JGG, and Zoological Research, etc.
- Published over 200 papers as corresponding author in premier journals, including 8 in Cell, 1 in Nature, and 43 in their affiliated journals.
- Citations exceed 18,513 with an H-index of 71.
- Research recognized twice as China's Top 10 Science Advances and four times as China's Top 10 Life Science Advances.
Research Interests
Jing Qu is mainly engaged in stem cell and aging. Cells across different organs undergo a transition into a state of senescence, and the accumulation of such cells in different organs is a part of the aging process. These senescent cells play a role in the structural and functional decline of organs and are associated with degenerative diseases. Jing Qu is comitted to investigating the properties of senescent cells, as well as their driving factors. Her research interest is to develop intervention strategies to manage cellular senescence and the degeneration in organ structure and functionality.
Selected Publications
1.Vitamin C inhibits ACSL4 to alleviate ferro-aging in primates. Cell Metabolism. 2026.
2.Systematic profiling reveals betaine as an exercise mimetic for geroprotection. Cell . 2025.
3.Nuclear-lamin-guided plastic positioning and folding of the human genome. Cell Reports. 2025.
4.The Sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA. Developmental Cell. 2024.
5.Resurrection of endogenous retroviruses during aging reinforces senescence. Cell . 2023.
6.Longevity secret - a pluripotent superpower. Cell Metabolism. 2022.
7.A Single-cell Transcriptomic Atlas of Primate Pancreatic Islet Aging. National Science Review. 2021.
8.Single-Cell Transcriptomic Atlas of Primate Ovarian Aging. Cell. 2020. (Cover story)
9.METTL3 counteracts premature aging via m6A-dependent stabilization of MIS12 mRNA. Nucleic Acids Research. 2020.