Prof. Ilya Bezprozvanny, University of Texas Southwestern Medical Center at Dallas, USA
invited by State Key Laboratory of Biomembrane and Membrane Biotechnology

Topic: "Calcium signaling and neurodegenerative disorders"
Subject: Neuroscience and Integrative Biology
Visiting Time: May 9-14, 2010

Abstract: Calcium ion (Ca²⁺) is a highly versatile intracellular signal that operates over a wide temporal range to regulate many different cellular processes, including fertilization, brain function, memory formation, gene transcription, cell proliferation, and cell death. As an ion messenger, cytosolic Ca²⁺ increases must be accurately controlled to achieve the signal fidelity upon stimulation. Failure of this calcium signaling system relates to many human diseases, such as hypertension, heart disease, diabetes, etc. Recently we have uncovered links between dysregulation of Ca²⁺ signaling and neurodegenerative disorders such as Huntington’s disease and Alzheimer’s disease. We hope that these findings may help in developing therapeutics for these incurable disorders.

Further Information: Ilya Bezprozvanny's Lab Homepage...

Prof. Ilya Bezprozvanny