Rho GTPases: physiological functions and therapeutic targeting

　　by Prof. ZHENG Yi, Director, Division of Experimental Hematology and Cancer Biology,

　　Katherine Stewart Waters Endowed Chair Professor of Pediatrics, University of Cincinnati College of Medicine

　　Tme: 10 : 00 am, 10 June. 2010 (Thu.) 

　　Place: Lecture Hall B105, Institute of Zoology, Chinese Academy of Sciences

　　Contact: Prof. LIN, Xin-Hua, 010-64807978

　　Introduction: Dr. Zheng was graduated from Tsinghua University in 1986 (B.S. in Chemistry), and finished his Ph.D in Cornell University in 1991. Dr. Yi Zheng is currently a Katherine Stewart Waters Endowed Chair Professor, and the Director of Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Research Foundation, USA. His lab has been focused on studies of the function and mechanism of regulation of the Rho family small GTP-binding proteins of Ras superfamily.  The Rho GTPases are a class of intracellular signal transducers that play important roles in normal development, stem cell maintenance and development of various cancers. By using a variety of current cellular, molecular, biochemical, and mouse genetic approaches, Dr. Zheng lab’s studies have elucidated many important functions of Rho GTPase proteins in various normal development and cancers  and have developed novel therapeutic reagents that may interfere with specific Rho pathways related to human diseases. Dr. Zheng has published more than 150 research papers in top journals including Science, Nature Medicine, J. Clin. Invest, Proc. Natl. Acad. Sci.

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