Title：Sex hormone-binding globulin: beyond plasma transport

　　Time：10:40am, 13 Nov. 2009 (Fri.)

　　Place：Lecture Hall  B-517, INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES

　　Contact：Hongmei WANG (64807187) / Haiyan LIN (64807189)

 

Dr. Geoffrey L. Hammond is recognized internationally as an expert in the area of steroid hormone action. He has published more than 300 scientific articles and reviews. He has served on numerous editorial boards and organizing committees of international meetings. He holds several patents and many of the reagents he has produced and methods he has developed are used world wide as diagnostic tools. In 1999, he served as VP Research and Development for Perkin Elmer Life Sciences, and has worked as consultant with numerous biotechnology and pharmaceutical companies.

Selected publication:

1. Selva DM, Hogeveen KN, Innis SM, Hammond GL (2007) Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene. J Clin Invest 117:3979-87.

2. Selva DM, Hogeveen KN, Hammond GL (2005) Repression of the human sex hormone-binding globulin gene in Sertoli cells by USF transcription factors. J Biol Chem 280:4462-4468.

3. Hogeveen KN, Cousin P, Pugeat M, Dewailly D, Soudan B, Hammond GL (2002) Human sex hormone-binding globulin variants associated with hyperandrogenism and ovarian dysfunction. J Clin Invest 109:973-81.

4. Hammond GL (1990) Molecular properties of corticosteroid binding globulin and the sex-steroid binding proteins. Endocr Rev 11:65-79.

5. Hammond GL, Smith CL, Goping IS, Underhill DA, Harley MJ, Reventos J, Musto NA, Gunsalus GL, Bardin CW (1987) Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors. Proc Natl Acad Sci U S A 84:5153-7.