Speaker: Dr. Jay Baltz

　　　　　Associate Director and Senior Scientist, Ottawa Health Research Institute

　　　　　Professor of Obstetrics & Gynecology, and Cellular & Molecular Medicine, University of Ottawa

Tme: 10: 00 am, 24 Nov. 2009 (Tue.) 

Place: Lecture Hall B517, Institute of Zoology, Chinese Academy of Sciences

Welcome　！

 State Key Laboratory of Reproductive Biology

Dr. Jay Baltz is a Senior Scientist and Associate Director of the Ottawa Hospital Research Institute, and Professor and Director of Basic Research of the Department of Obstetrics and Gynecology at the University of Ottawa. He is a member of the Institute Advisory Board of the CIHR Institute of Human Development, Child and Youth Health and Director of the CIHR Reproduction, Early Development, and the Impact on Health (REDIH) Training Program. 

Dr. Baltz received his BA in Physics from the University of Pennsylvania and PhD in Biophysics from The Johns Hopkins University. His postdoctoral training was in Dr. John Biggers’s group at Harvard Medical School, where he investigated early embryo physiology.

Dr. Baltz’s current research interests are in transport processes, cell volume regulation, other homeostatic mechanisms in growing and maturing oocytes and preimplantation embryos, and epigenetic regulation through methylation in blastocysts, and their role in producing healthy oocytes and embryos.

Selected Publications:

Tartia AP; Rudraraju N; Richards T; Hammer MA; Talbot P; Baltz JM, (2009 Jul), Cell volume regulation is initiated in mouse oocytes after ovulation, Development, Vol.136, Issue 13, 2247-2254

Anas MK; Lee MB; Zhou C; Hammer MA; Slow S; Karmouch J; Liu XJ; Broer S; Lever M; Baltz JM, (2008 Dec), SIT1 is a betaine/proline transporter that is activated in mouse eggs after fertilization and functions until the 2-cell stage, Development, Vol.135, Issue 24, 4123-4130

FitzHarris G; Siyanov V; Baltz JM, (2007), Granulosa cells regulate oocyte intracellular pH against acidosis in preantral follicles by multiple mechanisms, Development, Vol.134, Issue 23, 4283-4295

Fitzharris G; Baltz JM, (2006 Feb), Granulosa cells regulate intracellular pH of the murine growing oocyte via gap junctions: development of independent homeostasis during oocyte growth, Development , Vol.133, Issue 4, 591-599

Erdogan S; FitzHarris G; Tartia AP; Baltz JM, (2005), Mechanisms regulating intracellular pH are activated during growth of the mouse oocyte coincident with acquisition of meiotic competence, Dev Biol , Vol.286, Issue 1, 352-360

Steeves CL; Hammer MA; Walker GB; Rae D; Stewart NA; Baltz JM, (2003 Nov 25), The glycine neurotransmitter transporter GLYT1 is an organic osmolyte transporter regulating cell volume in cleavage-stage embryos, Proceedings of the National Academy of Sciences of the United States of America, Vol.100, Issue 24, 13982-13987

Phillips KP; Petrunewich MA; Collins JL; Baltz JM, (2002 Nov), The intracellular pH-regulatory HCO3-/Cl- exchanger in the mouse oocyte is inactivated during first meiotic metaphase and reactivated after egg activation via the MAP kinase pathway, Molecular Biology of the Cell, Vol.13, Issue 11, 3800-3810

Phillips KP; Petrunewich MA; Collins JL; Booth RA; Liu XJ; Baltz JM, (2002 Jul 1), Inhibition of MEK or cdc2 kinase parthenogenetically activates mouse eggs and yields the same phenotypes as Mos(-/-) parthenogenotes, Developmental Biology, Vol.247, Issue 1, 210-223

Kolajova M; Hammer MA; Collins JL; Baltz JM, (2001 Sep), Developmentally regulated cell cycle dependence of swelling-activated anion channel activity in the mouse embryo, Development, Vol.128, Issue 18, 3427-3434