Title：Stoicheiometry of calcium-released activated calcium channel.

Speaker：Prof. CHEN Liang-yi 

Time：2012.7.25 3:00pm

Place：IOZ C101

Selected Publications：

1. Li Z, Liu L, Deng Y, Ji W, Du W, Xu P, Chen L*, Xu T*. Graded activation of Orai1 subunits by different numbers of STIM1 leads to multistate opening of the CRAC channel. Cell Research. 2011, 21:305-315.

2. Ji W, Xu P, Li Z, Lu J, Liu L, Zhan Y, Chen Y, Hille B, Xu T*, Chen L*. Functional stoichiometry of the unitary calcium-release-activated calcium channel. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13668-73.

3. He Z, Fan J, Kang L, Lu J, Xue Y, Xu P, Xu T*, Chen L*. Ca2+ triggers a novel clathrin-independent but actin-dependent fast endocytosis in pancreatic beta cells. Traffic. 2008 Jun;9(6):910-23.

4. Li Z, Lu J, Xu P, Xie X, Chen L*, Xu T*. Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation. J Biol Chem. 2007;282(40):29448-29456. 5. Chen L, Koh DS. and Hille B. Dynamics of calcium clearance in mouse pancreatic beta cells. Diabetes 2003, 52: 1723-1731

Contact： Prof. TANG Tie-shan （64807296，tangtsh@ioz.ac.cn）