Title：Surprising roles of epigenetic regulation in pluripotent stem cells Speaker：Andrew Xiao Ph.D, Yale University Dr. Xiao is an assistant professor in the Department of Genetics at the Yale University School of Medicine. He is a member of the Yale Stem Cell Center. Dr. Xiao’s laboratory focuses on epigenetic regulation in pluripotentstem cells, including embryonic stem cells and induced pluripotenctstem cells (iPSC), as well as epigenetic regulation in neural development and aging. Dr. Xiao received his Ph.Ddegree from Terry Van Dyke’s lab at UNC-Chapel Hill and postdoctoral training from David Allis’ lab at Rockefeller University. Since 2009, Andrew Xiao is a recipient of the NCI Howard Temin Award in Cancer Research (K99/R00) and in 2012, he received the New Scholar Award from the Ellison Medical Foundation. Selected publications：Wu T, StadtfeldM, Tseng Z, Liu Y, TahmasianM, HochedlingerK & Xiao A*. HistoneVariant H2A.X-Mediated Epigenetic Mechanisms are Critical for Maintaining Genome Stability and Pluripotencyin ES and iPSCells. (2014) Cell Stem Cell15(3):281-294Dai J., Liu Y., Na L., ChioureaM., OkukaM., Wu T, ChunlinM., Wang L, Wang L, Yin Y., Yuan J., ZuoB., Wang F., Ye X., Li Z, Pan X., Yin Z., Chen L., Keefe D.J., GagosS., Xiao A.* and Liu L* Rif1 Maintains Telomere Length Homeostasis of Embryonic Stem Cells by Mediating SubtelomericHeterochromatin Silencing. (2014) Developmental Cell 29(1) 7-19Xiao A., Li H., ShechterD., AhnS.H.,. FabrizioL.A., Erdjument-BromageH., Ishibe-Murakami S., Wang B., TempstP., Hoffman K., Patel D.J., Elledge, S.J., and Allis C.D. (2009) WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinaseactivity. Nature(research article) 457, 57-62. Time：2014.11.3, 3pm Place：IOZ-B105 
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The 5th International Conference on Rodent Biol...
