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Name:
 QU Jing
Subject:
 Regenerative medicine
Tel/Fax:
 +86-10-64807768  / 
E-mail:
 qujing@ioz.ac.cn
Address:
 State Key Laboratory of Stem Cell and Reproductive Biology Institute of Zoology, CAS. Beichen West Road 1#, Chaoyang District, Beijing, China. 100101
More:
 Group of Stem cell and Aging      
Resume:

Jing Qu earned her B.S. from Lanzhou University in 2002, and then the doctor degree from the Institute of Biophysics, CAS in 2007. From 2007 to 2012, she worked as a Postdoctoral Fellow at the Del E. Web Neuroscience, Aging, and Stem Cell Research Center at the Sanford/Burnham Medical Research Institute, and then as a Research Associate in the Gene Expression Laboratory at the Salk Institute for Biological Studies. Since 2014, she established the “ Stem Cell and Aging” Lababory at the Institute of Zoology, CAS. She is now the Chair of the Aging Genetics Elites of the Genetics Society of China, and also a member of Scientific Program Committee of ISSCR. She received the Chinese Young Women in Science Fellowship for her contributions to aging research.

Research Interests:

Jing Qu is mainly engaged in stem cell and aging. Cells across different organs undergo a transition into a state of senescence, and the accumulation of such cells in different organs is a part of the aging process. These senescent cells play a role in the structural and functional decline of organs and are associated with degenerative diseases. Jing Qu is comitted to investigating the properties of senescent cells, as well as their driving factors. Her research interest is to develop intervention strategies to manage cellular senescence and the degeneration in organ structure and functionality.

Awards and Honors:

Professional Activities:

Research Grants:

Selected Publications:
  1. The Sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA. Developmental Cell. 2024.
  2. Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation. Cell Stem Cell. 2023.
  3. Longevity secret - a pluripotent superpower. Cell Metabolism. 2022.
  4. Destabilizing heterochromatin by APOE mediates senescence. Nature Aging. 2022.
  5. A Single-cell Transcriptomic Atlas of Primate Pancreatic Islet Aging. National Science Review. 2021.
  6. SIRT3 consolidates heterochromatin and counteracts senescence. Nucleic Acids Research. 2021.
  7. A Single-Cell Transcriptomic landscape of Primate Arterial Aging. Nature Communications. 2020.
  8. Single-Cell Transcriptomic Atlas of Primate Ovarian Aging. Cell. 2020. (Cover story)
  9. Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging. Cell. 2020.