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Name:
 JIN Jianshi
Subject:
 Biotechnology/Genomics/Molecular Biology
Tel/Fax:
 +86-10-64807550  / 
E-mail:
 jinjs@ioz.ac.cn
Address:
 The State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
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Resume:

2023 – present Professor, Institute of Zoology, Chinese Academy of Sciences, China

2016 – 2023 Senior Scientist/Research Scientist/JSPS Postdoctoral Fellowship, RIKEN Center for Biosystems Dynamics Research (BDR), Japan.

2014 – 2016 Postdoctoral fellowship, BIOPIC, School of Life Science, Peking University, China.

Education:

2009 – 2014 Ph.D. in Biomechanics and medical engineering; BIOPIC & Academy for Advanced Interdisciplinary Studies, Peking University, China.

2010 – 2011 Visiting Student; Sunney Xie group, Department of Chemistry and Chemical Biology, Harvard University, USA.

2005 – 2009 B. S. in Chemistry; School of Chemistry and Chemical Engineering, Nanjing University, China.

Research Interests:

　　Jin lab will develop and apply single-cell technologies to study the functions of unknown bacteria and the mechanism of bacteria-host interactions in the guts of important agricultural and sanitarily harmful animals. Furthermore, the discovered functional bacteria in the gut will then be investigated to regulate the phenotypes of the animals.

Awards and Honors:

Professional Activities:

Research Grants:

Selected Publications:

（#corresponding; *equal contribution）：

12. Jianshi Jin#, Reiko Yamamoto, Katsuyuki Shiroguchi#, High-throughput identification and quantification of bacterial cells in the microbiota based on 16S rRNA sequencing with single-base accuracy using BarBIQ. Nature Protocols, 2023, https://doi.org/10.1038/s41596-023-00906-8.

11. Jianshi Jin*, Taisaku Ogawa*, Nozomi Hojo, Kirill Kryukov, Kenji Shimizu, Tomokatsu Ikawa, Tadashi Imanishi, Taku Okazaki, Katsuyuki Shiroguchi, Robotic data acquisition with deep learning enables cell image-based prediction of transcriptomic states. Proceedings of the National Academy of Sciences USA, 120 (1), e2210283120, 2023.

10. Guangwei Cui, Akihiro Shimba, Jianshi Jin, Nozomi Hojo, Takuma Asahi, Shinya Abe, Aki Ejima, Shinri Okada, Keizo Ohira, Ryoma Kato, Shizue Tani-ichi, Ryo Yamada, Takashi Ebihara, Katsuyuki Shiroguchi, Koichi Ikuta, CD45 alleviates airway inflammation and lung fibrosis by limiting expansion and activation of ILC2s. Proceedings of the National Academy of Sciences USA, 120 (36), e2215941120, 2023.

9. Sonoko Takahashi, Sotaro Ochiai, Jianshi Jin, Noriko Takahashi, Susumu Toshima, Harumichi Ishigame, Kenji Kabashima, Masato Kubo, Manabu Nakayama, Katsuyuki Shiroguchi, and Takaharu Okada, Sensory neuronal STAT3 is critical for IL-31 receptor expression and inflammatory itch. Cell Reports, 113433, 2023.

8. Jianshi Jin, Reiko Yamamoto, Tadashi Takeuchi, Guangwei Cui, Eiji Miyauchi, Nozomi Hojo, Koichi Ikuta, Hiroshi Ohno, Katsuyuki Shiroguchi, High-throughput identification and quantification of single bacterial cells in the microbiota. Nature communications, 13:863, 2022.

7. Guangwei Cui, Akihiro Shimba, Jianshi Jin, Taisaku Ogawa, Yukiko Muramoto, et al. A circulating subset of iNKT cells mediates antitumor and antiviral immunity. Science Immunology, 7, eabj8760, 2022.

6. Yanmeng Li, Jianshi Jin, Fan Bai, Cancer biology deciphered by single-cell transcriptomic sequencing, Protein Cell, 13(3):167–179, 2022.

5. Katsuyuki Shiroguchi *, Jianshi Jin*, and Reiko Yamamoto, Method for treating cell population and method for analyzing genes included in cell population. Application No.: PCT/JP2021/020338.

4. Jianli Tao*, Xiao-Wei Zhang*, Jianshi Jin*, Xiao-Xia Du, Tengfei Lian, Jing Yang, Xiang Zhou, Zhengfan Jiang and Xiao-Dong Su, Nonspecific DNA Binding of cGAS N Terminus Promotes cGAS Activation. The Journal of Immunology, 198(9):3627-3636, 2017.

3. Jianshi Jin*, Tengfei, Lian*, Chan Gu*, Kai Yu, Yi Qin Gao & Xiao-Dong Su, The effects of cytosine methylation on general transcriptional factors. Scientific Reports, 6:29119, 2016.

2. Jianshi Jin, Tengfei, Lian, X. Sunney Xie, Xiao-Dong Su, High-accuracy mapping protein binding stability on nucleosomal DNA using single-molecule method. Journal of Molecular Cell Biology, 6(5):438-40, 2014.

1. Sangjin Kim,* Erik Brostromer,* Dong Xing,* Jianshi Jin,* Shasha Chong, Hao Ge, Siyuan Wang, Chan Gu, Lijiang Yang, Yi Qin Gao, Xiao-dong Su, Yujie Sun, X. Sunney Xie, Probing Allostery Through DNA, Science, 339:816-819, 2013.