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Name: |
TAN Weiqi
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Subject: |
Cell Biology |
Tel/Fax: |
+86-10-64807318
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E-mail: |
tanwq@ioz.ac.cn |
Address: |
Institute of Zoology, Chinese Academy of Sciences (CAS). Institute for Stem Cell and Regenerative Medicine, CAS, Yard A 3, Datun Road, Chaoyang District, Beijing 100101, P. R. China |
More: |
Group of Immunity and Signal Transduction
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| Resume: |
Education: 2002.1-2005.1 Ph.D. Molecular Biology, The Hong Kong Polytechnic University, Hong Kong, P. R. China 1993.9-1996.8 M.Phil. Biochemistry, The Hong Kong University of Science and Technology, Hong Kong, P. R. China 1984.9-1988.7 B.S. Biochemistry, Peking University, Beijing, P. R. China Employment: 2011.1-Now Associate Professor, Institute of Zoology, Chinese Academy of Sciences 2009.2-2011.1 Visiting Scientist, UT MD Anderson Cancer Center 2001.2-2001.8 Visiting Scholar, The Hong Kong University of Science and Technology 1996.9-2009.1 Assistant Professor, Institute of Zoology, Chinese Academy of Sciences 1988.7-1993.8 Research assistant, Institute of Zoology, Chinese Academy of Sciences |
| Research Interests: |
Investigate the regulatory mechanism of microRNA methylation on disease-related genes. |
| Selected Publications: |
- Cheng, Y.#, Wang, Z. M.#, Tan, W. #, Wang, X.#, Li, Y., Bai, B., Li, Y., Zhang, S. F., Yan, H. L., Chen, Z. L., Liu, C. M., Mi, T. W., Xia, S., Zhou, Z., Liu, A., Tang, G. B., Liu, C., Dai, Z. J., Wang, Y. Y., Wang, H., Wang, X., Kang, Y., Lin, L., Chen, Z., Xie, N., Sun, Q., Xie, W., Peng, J., Chen, D., Teng, Z. Q., and Jin, P. (2018) Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a. Nat Neurosci 21, 1689-1703 (#, cofirst auther)
- Jin, W., Wang, L., Zhu, F., Tan, W., Lin, W., Chen, D., Sun, Q., and Xia, Z. (2016) Critical POU domain residues confer Oct4 uniqueness in somatic cell reprogramming. Sci Rep 6, 20818
- Tan, W., Gu, J., Huang, M., Wu, X., and Hildebrandt, M. A. (2015) Epigenetic analysis of microRNA genes in tumors from surgically resected lung cancer patients and association with survival. Mol carcinog 54 Suppl 1, E45-51
- Zhu, G., Li, Y., Zhu, F., Wang, T., Jin, W., Mu, W., Lin, W., Tan, W., Li, W., Street, R. C., Peng, S., Zhang, J., Feng, Y., Warren, S. T., Sun, Q., Jin, P., and Chen, D. (2014) Coordination of engineered factors with TET1/2 promotes early-stage epigenetic modification during somatic cell reprogramming. Stem cell reports 2, 253-261
- Hildebrandt, M. A., Tan, W., Tamboli, P., Huang, M., Ye, Y., Lin, J., Lee, J. S., Wood, C. G., and Wu, X. (2012) Kinome expression profiling identifies IKBKE as a predictor of overall survival in clear cell renal cell carcinoma patients. Carcinogenesis 33, 799-803
- Tan, W., Hildebrandt, M. A., Pu, X., Huang, M., Lin, J., Matin, S. F., Tamboli, P., Wood, C. G., and Wu, X. (2011) Role of inflammatory related gene expression in clear cell renal cell carcinoma development and clinical outcomes. J Urol 186, 2071-2077
- Hildebrandt, M. A., Gu, J., Lin, J., Ye, Y., Tan, W., Tamboli, P., Wood, C. G., and Wu, X. (2010) Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma. Oncogene 29, 5724-5728
- Tan, W., Wang, J. X., Lin, Z. Q., Li, Y. R., Lin, Y., and Li, P. F. (2008) Novel cardiac apoptotic pathway: the dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin. Circulation 118, 2268-2276
- Tan, W., Wang, K., Lv, D.Y., and Li, P.F. (2008) Foxo3a inhibits cardiomyocyte hypertrophy through transactivating catalase. J Biol Chem 283, 29730-29739
- Tan, W., Gou, D. M., Tai, E., Zhao, Y. Z., and Chow, L. M. (2006) Functional reconstitution of purified chloroquine resistance membrane transporter expressed in yeast. Arch Biochem Biophys 452, 119-128
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