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Name:
 Ji, Fen
Subject:
 Developmental Biology
Tel/Fax:
 +86-10-64806229  / 
E-mail:
 jifen@ioz.ac.cn
Address:
 The State Key Laboratory of Stem cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
More:
 Group of Neural Stem Cell and Neurogenesis      
Resume:
Ji Fen, associate professor of Institute of Zoology, Chinese Academy of Sciences. She obtained a Ph.D. in Beijing Institute of Genomics, Chinese Academy of Science in 2008. Ji Fen held a postdoctoral position in Institute of Microbiology, Chinese Academy of Science from 2008 to 2011. She joined the Group of Neural Stem cell and Neurogenesis in 2011 as assistant professor and promoted associate professor in Institute of Zoology in 2019. The research direction is to reveal the mechanisms involving neural stem cell proliferation and neurogenesis during the brain development.

Research Interests:

Awards and Honors:

Professional Activities:

Research Grants:
  • Youth Program of National Natural Science Foundation of China (31300894)
  • National Key Research and Development Project (2014CB964600)
  • National Key Research and Development Project (2019YFA0110300)
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    Selected Publications:
    1. Fen Ji; Wenwen Wang; Chao Feng; Fei Gao; Jianwei Jiao*. Brain-specific Wt1 Deletion Leads to Depressive-like Behaviors in Mice via the Recruitment of Tet2 to Modulate Epo Expression. Molecular Psychiatry, 2020.
    2. Feng Chao, Zhao Jinyue, Ji Fen, Su Libo, Chen Y, Jiao Jianwei*. TCF20 dysfunction leads to cortical neurogenesis defects and autistic-like behaviors in mice. EMBO Rep. 2020.
    3. Huimin Qiao#; Yanxin Li#; Chao Feng; Shuguang Duo; Fen Ji*; Jianwei Jiao*. Nap1l1 Controls Embryonic Neural Progenitor Cell Proliferation and Differentiation in the Developing Brain. Cell Reports, 2018, 22: 2279-2293.
    4. Tianjin Shen; Fen Ji; Yuanyuan Wang; Xuepei Lei; Dongming Zhang; Jianwei Jiao*. Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder. Nucleic Acids Research, 2018, 46(5): 2290-2307.
    5. Ji, Fen#; Shen, Tianjin#; Zou, Wenzheng; Jiao, Jianwei*. UCP2 Regulates Embryonic Neurogenesis via ROS-mediated Yap Alternation in the Developing Neocortex. Stem Cells, 2017, 35: 1479-1492.
    6. Shukun Wang#; Qingli Liang#; Huimin Qiao; Hong Li; Tianjin Shen; Fen Ji; Jianwei Jiao*. DISC1 Regulates Astrogenesis in the Embryonic Brain via Modulation of RAS/MEK/ERK Signaling Through RASSF7. Development, 2016, 143(15): 2732-2740.
    7. Tianjin Shen#; Fen Ji#; Zengqiang Yuan; Jianwei Jiao*. CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex. Stem cells, 2015, 33: 1794-1806.
    8. Shen Tianjin; Ji Fen; Jiao Jianwei*. Epigenetics: major regulators of embryonic neurogenesis. Science Bulletin, 2015, 60(20): 1734-1743.
    9. Zhang Juan#; Ji Fen#; Liu Yanli; Lei Xuepei; Li Hong; Ji Guangju; Yuan Zengqiang; Jiao Jianwei*. Ezh2 Regulates Adult Hippocampal Neurogenesis and Memory. Journal of Neuroscience, 2014, 34(15): 5184-5199.
    10. Wang Shukun#; Li Baoguo#; Qiao Huimin; Lv Xiaohui; Liang Qingli; Shi Zixiao; Xia Wenlong; Ji Fen; Jiao Jianwei*. Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex. EMBO Reports, 2014, 15(10): 1053-1061.
    11. Ji Fen; Lv Xiaohui; Jiao Jianwei*. The Role of microRNAs in Neural Stem Cells and Neurogenesis. Journal of Genetics and Genomics, 2013, 40(2): 61-66.
    12. Ji Fen; Yang Bin; Peng Xiangxin; Ding Huiguo; You Hong; Tien Po*. Circulating microRNAs in hepatitis B virus-infected patients. Journal of Viral Hepatitis, 2011, 18(7): E242-E251.
    13. Ji Fen; Zhou Li; Ma Sufang; Li Feifei; Ding Huiguo; Zeng Changqing*. Dynamic Changes of HBV Quasispecies and Deletion Patterns in a Chronic Hepatitis B Patient. Journal of Medical Virology, 2009, 81(9): 1551-1559.