Yanxia Ye----Institute of Zoology Chinese Academy of Sciences

Name:	Yanxia Ye
Subject:	Cellular Biology of Aging
Tel/Fax:	+86-10-64807583 /
E-mail:	yeyanxia@ioz.ac.cn
Address:	State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Stem Cell and Regeneration, Chinese Academy of Sciences, Yard A 3, Datun Road, Chaoyang District, Beijing 100101, China
More:	Group of Stem cell and Aging

Resume:

Yanxia Ye, Associate Professor of Institute of Zoology, Chinese Academy of Sciences.

Research Experience

2024.02-Now，Associate Professor, Institute of Zoology, Chinese Academy of Sciences

2016.01-2024.01，Assistant Professor, Institute of Zoology, Chinese Academy of Sciences

2012.10-2016.01，Postdoctoral fellow, Department of Rheumatology and Clinical Immunology, Chinese Academy of Medical Sciences and Peking Union Medical College

Research Interests:

Dr. Yanxia Ye is dedicated to studying aging and associated diseases in the immune, circulatory, and cardiovascular systems. She employs techniques such as human stem cells, non-human primate models, single-cell sequencing, multi-omics approaches, and gene editing to systematically analyze the molecular mechanisms and interventions related to aging and associated diseases.

Awards and Honors:

Professional Activities:

Research Grants:

Selected Publications:

Yanxia Ye^#, Kuan Yang^#, Haisong Liu^#, Yang Yu^#, Moshi Song^#, Daoyuan Huang, Jinghui Lei, Yiyuan Zhang, Zunpeng Liu, Qun Chu, Yanling Fan, Sheng Zhang, Yaobin Jing, Concepcion Rodriguez Esteban, Si Wang, Juan Carlos Izpisua Belmonte, Jing Qu*, Weiqi Zhang*, Guang-Hui Liu*. SIRT2 counteracts primate cardiac aging via deacetylation of STAT3 that silences CDKN2B. Nature Aging. 2023. 3(10): 1269-1287. (Cover story)
Shuai Ma^#, Si Wang^#, Yanxia Ye^#, Jie Ren, Ruiqing Chen, Wei Li, Jiaming Li, Liyun Zhao, Qian Zhao, Guoqiang Sun, Ying Jing, Yuesheng Zuo, Muzhao Xiong, Yuanhan Yang, Qiaoran Wang, Jinghui Lei, Shuhui Sun, Xiao Long, Moshi Song, Shuyang Yu, Piu Chan, Jianwei Wang, Qi Zhou, Juan Carlos Izpisua Belmonte, Jing Qu*, Weiqi Zhang*, Guang-Hui Liu*. Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues. Cell Stem Cell. 2022. 29(6):990-1005.e10.
Shuai Ma^#, Shuhui Sun^#, Lingling Geng^#, Moshi Song^#, Wei Wang, Yanxia Ye, Qianzhao Ji, Zhiran Zou, Si Wang, Xiaojuan He, Wei Li, Concepcion Rodriguez Esteban, Xiao Long, Guoji Guo, Piu Chan, Qi Zhou, Juan Carlos Izpisua Belmonte*, Weiqi Zhang*, Jing Qu*, and Guang-Hui Liu*. Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging. Cell. 2020. 180, 1–18.
Shuyan Wang^#, Zhongfeng Liu^#, Yanxia Ye^#, Bingnan Li, Tiantian Liu, Weiqi Zhang, Guang-Hui Liu, Y. Alex Zhang, Jing Qu*, Dawei Xu*, Zhiguo Chen*, Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model. Cell Death Dis. 2018. 9(9): 923.
LiDan Zhao, YanXia Ye, Xuan Zhang*. B cells biology in systemic lupus erythematosus-from bench to bedside. Sci China Life Sci. 2015. 58, 1111-1125.
Xiangni Wu^#, Yanxia Ye^#, Jingwen Niu^#, Yang Li, Xin Li, Xin You, Hua Chen, Li-dan Zhao, Xiaofeng Zeng, Fengchun Zhang, Fulin Tang, Wei He, Xuetao Cao, Xuan Zhang*, Peter E Lipsky*. Defective PTEN regulation contributes to B cell hyperreponsiveness in systemic lupus erythematosus. Sci Transl Med. 2014. 23;6(246): 246ra99.
Yanxia Ye, Xiuyan Huang, Yaxing Zhang, Xinqiang Lai, Xiaoping Wu, Xiangfeng Zeng, Xiangao Tang, Yaoying Zeng*. Calcium influx blocked by SK&F 96365 modulates the LPS plus IFN-<gamma>-induced inflammatory response in murine peritoneal macrophages. International immunophamacology. 2012. 12(2):384-93.
Yanxia Ye, Yaxing Zhang, Xiaoyu Lu, Xiuyan Huang, Xiangfeng Zeng, Xinqiang Lai, Yaoying Zeng*. The anti-inflammatory effect of the SOCC blocker SK&F 96365 on mouse lymphocytes after stimulation by Con A or PMA/ionomycin. Immunobiology. 2011. 216(9):1044-53.