 |
Name: |
Ren, Xianwen
|
Subject: |
Single-cell Bioinformatics |
Tel/Fax: |
/
|
E-mail: |
renxwise@ioz.ac.cn |
Address: |
No.3 Jia Yard Datun Road, Chaoyang District, Institute of Zoology, Chinese Academy of Sciences, Beichen West Road #1, Chaoyang District, Beijing, China, 100101 |
More: |
|
|
| Resume: |
Education 2007-2010 Academy of Mathematics and Systems Sciences, Chinese Academy of Sciences，Operation Research, PhD 2004-2007 Beijing Institute of Biotechnology, Genetics, Master 2000-2004 Nankai University, Life Sciences, Information and Computation Sciences, Bachelors Research and Work Experience 2025-present Institute of Zoology, Chinese Academy of Sciences, Professor 2021-2025 Changping Laboratory, Professor 2016-2021 BIOPIC, Peking University, Associate Professor 2013-2016 Institute of Pathogen Biology, Chinese Academy of Medical Sciences，Associate Professor 2010-2013 Institute of Pathogen Biology, Chinese Academy of Medical Sciences，Assistant Professor 2008-2009 The Methodist Hospital Research Institute, Cornell University, Visiting Scholar |
| Research Interests: |
My research interest is developing AI algoirthms to build virtual/digital cells/organs to answer immunological questions of various diseases including cancer, infection, and injury. |
| Awards and Honors: |
2022 VCANBIO, Award for Biosciences and Medicine 2020 Nature Sciences Prize, Beijing (1st Class) 2016 Outstanding Science and Technology Achievements Award, MOE (1st Class) 2014 Outstanding Award of Peking Union Medical College |
| Selected Publications: |
(#, first author; *, corresponding author) - Ren Xianwen(#), Wen Wen(#), Fan Xiaoying(#), Hou Wenhong(#), Su Bin(#), Cai Pengfei(#), Li Jiesheng(#), Liu Yang(#), Tang Fei(#), Zhang Fan(#), Yang Yu(#), He Jiangping(#), Ma Wenji(#), He Jingjing(#), Wang Pingping(#), Cao Qiqi, Chen Fangjin, Chen Yuqing, Cheng Xuelian, Deng Guohong, Deng Xilong, Ding Wenyu, Feng Yingmei, Gan Rui, Guo Chuang, Guo Weiqiang, He Shuai, Jiang Chen, Liang Juanran, Li Yi-min, Lin Jun, Ling Yun, Liu Haofei, Liu Jianwei, Liu Nianping, Liu Shu-Qiang, Luo Meng, Ma Qiang, Song Qibing, Sun Wujianan, Wang GaoXiang, Wang Feng, Wang Ying, Wen Xiaofeng, Wu Qian, Xu Gang, Xie Xiaowei, Xiong Xinxin, Xing Xudong, Xu Hao, Yin Chonghai, Yu Dongdong, Yu Kezhuo, Yuan Jin, Zhang Biao, Zhang Peipei(#), Zhang Tong, Zhao Jincun, Zhao Peidong, Zhou Jianfeng, Zhou Wei, Zhong Sujuan, Zhong Xiaosong, Zhang Shuye, Zhu Lin, Zhu Ping, Zou Bin, Zou Jiahua, Zuo Zengtao, Bai Fan, Huang Xi, Zhou Penghui(*), Jiang Qinghua(*), Huang Zhiwei(*), Bei Jin-Xin(*), Wei Lai(*), Bian Xiu-Wu(*), Liu Xindong(*), Cheng Tao(*), Li Xiangpan(*), Zhao Pingsen(*), Wang Fu-Sheng(*), Wang Hongyang(*), Su Bing(*), Zhang Zheng(*), Qu Kun(*), Wang Xiaoqun(*), Chen Jiekai(*), Jin Ronghua(*), Zhang Zemin(*), COVID-19 immune features revealed by a large-scale single cell transcriptome atlas, Cell, 2021 Apr 1;184(7):1895-1913.e19.
- Ren Xianwen(*#), Zhong Guojie(#), Zhang Qiming, Zhang Lei, Sun Yujie, Zhang Zemin(*), Reconstruction of cell spatial organization from single-cell RNA sequencing data based on ligand-receptor mediated self-assembly, Cell Research, 2020.06.15, 30: 763–778
- Zhang Qiming(#), He Yao(#), Luo Nan(#), Patel Shashank J, Han Yanjie, Gao Ranran, Modak Madhura, Carotta Sebastian, Haslinger Christian, Kind David, Peet Gregory W, Zhong Guojie, Lu Shuangjia, Zhu Weihua, Mao Yilei, Xiao Mengmeng, Bergmann Michael, Hu Xueda, Kerkar Sid P, Vogt Anne B, Pflanz Stefan, Liu Kang(*), Peng Jirun(*), Ren Xianwen(*), Zhang Zemin(*), Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma, Cell, 2019.10.31, 179(4):829-845.e29
- Zhou Zixiang(#), Zhong Yunshan(#), Zhang Zemin, Ren Xianwen(*), Spatial transcriptomics deconvolution at single-cell resolution using Redeconve, Nature Communications 2023, 14 (1), 7930
- Zhang Chao(#), Li Jiesheng(#), Cheng Yongqian, Meng Fanping, Song Jin-Wen, Fan Xing, Fan Hongtao, Li Jing, Fu Yu-Long, Zhou Ming-Ju, Hu Wei, Wang Si-Yu, Fu Yuan-Jie, Zhang Ji-Yuan, Xu Ruo-Nan, Shi Ming, Hu Xueda, Zhang Zemin (*), Ren Xianwen (*), Wang Fu-Sheng (*), Single-cell RNA sequencing reveals intrahepatic and peripheral immune characteristics related to disease phases in HBV-infected patients, Gut, 2023 72 (1), 153-167.
- Ren Lili(#), Liu Yiwei(#), Wang Yeming(#), Wu Chao(#), Guo Li(#), Chen Lan, Wang Xinming, Xiao Yan, Huang Lixue, Zhong Jingchuan, Yao Jiacheng, Liu Lu, Li Hui, Wang Ying, Ma Yongchao, Zhang Yichunzi, Di Lin, Dong Tao, Knight Julian, Wang Jianbin(*), Huang Yanyi(*), Cao Bin(*), Ren Xianwen(*), Wang Jianwei, (*) Longitudinal landscape of immune reconstitution after acute SARS-CoV-2 infection at single-cell resolution, Science bulletin, 2025, 70 (3), 323-327
- Cong Boyi(#), Dong Xuan(#), Yang Zongheng(#), Yu Pin(#), Chai Yangyang, Liu Jiaqi, Zhang Meihan, Zang Yupeng, Kang Jingmin, Feng Yu, Liu Yi, Feng Weimin, Wang Dehe, Deng Wei, Li Fengdi, Song Zhiqi, Wang Ziqiao, Chen Xiaosu, Qin Hua, Yu Qinyi, Li Zhiqing, Liu Shuxun, Xu Xun, Zhong Nanshan, Ren Xianwen(*), Qin Chuan(*), Liu Longqi(*), Wang Jian(*), Cao Xuetao(*), Single-cell spatiotemporal analysis reveals alveolar dendritic cell–T cell immunity hubs defending against pulmonary infection, Cell Discovery 2024,10 (1), 103
- Cong Boyi(#), Dong Xuan(#), Yang Zongheng(#), Yu Pin(#), Chai Yangyang, Liu Jiaqi, Zhang Meihan, Zang Yupeng, Kang Jingmin, Feng Yu, Liu Yi, Feng Weimin, Wang Dehe, Deng Wei, Li Fengdi, Song Zhiqi, Wang Ziqiao, Chen Xiaosu, Qin Hua, Yu Qinyi, Li Zhiqing, Liu Shuxun, Xu Xun, Zhong Nanshan, Ren Xianwen(*), Qin Chuan(*), Liu Longqi(*), Wang Jian(*), Cao Xuetao(*), Single-cell spatiotemporal analysis of the lungs reveals Slamf9+ macrophages involved in viral clearance and inflammation resolution, Cell Discovery 2024,10 (1), 104
- Liu Yedan(#), Zhang Qiming(#), Xing Baocai(#), Luo Nan(#), Gao Ranran, Yu Kezhuo, Hu Xueda, Bu Zhaode, Peng Jirun(*), Ren Xianwen(*), Zhang Zemin(*), Immune phenotypic linkage between colorectal cancer and liver metastasis, Cancer Cell, 2022 Apr 11;40(4):424-437.e5.
- Liu Fengjie, Gao Yumei, Xu Bufang, Xiong Shan, Yi Shengguo, Sun Jingru, Chen Zhuojing, Liu Xiangjun, Li Yingyi, Lin Yuchieh, Wen Yujie, Qin Yao, Yang Shuxia, Li Hang, Tejasvi Trilokraj, Tsoi Lam, Tu Ping, Ren Xianwen (*), Wang Yang (*), PEG10 amplification at 7q21.3 potentiates large-cell transformation in cutaneous T-cell lymphoma, Blood, 2022 Jan 27;139(4):554-571
|
|
|
|
