IOZ actively promotes the transformation of science and technology achievements by integrating social resources and introducing enterprise mechanisms. A pilot-scale base named “Pilot-Scale Base of Bio-Pesticides, Institute of Zoology, Chinese Academy of Sciences” was co-constructed with Henan Jiyuan Baiyun Industry Co., Ltd. (HJBI), to develop baculoviral insecticides in 2003. Up to now, a series of high quality baculoviral insecticides, trademarked as KEYUN, were successfully developed and produced, including Helicoverpa armigera nucleopolyhedrovirus, Spodoptera exigua nucleopolyhedrovirus, S. litura nucleopolyhedrovirus and Plutella xylostella granulovirus. Eight types of products acquired the certificates of pesticide registry. These products mainly control damages caused by the cotton boll worm, beet armyworm, common cutworm and diamondback moth. These products do not have any bad influence on environment, and are safe to agricultural production. The capacity of the bio-insecticides can reach five ton for technical materials and 200 ton for formulations, the amount of which could be applied in the area of over two million ha. The corporation has been built the largest base for developing, producing and marketing the baculoviral insecticides in China. The bio-insecticide products had been extended to an area of over 300 thousand ha in the late three years in China, with the amount was equivalent to reducing application of approximate 450 ton chemical insecticide. This achievement was written in the CAS Year Report of 2008 as one of the Top 20 significant achievements in the field of science and technology.