Research Progress

• Inhibition of PDE10A rescues impaired social behavior, learning and memory in mice with partial loss of MIR137

  Nov 07, 2018
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  Research Shows Benefit of Giant Panda Conservation Far Exceeds Cost

  The giant panda is a flagship species of wildlife conservation worldwide, and its black and white pelage and cute appearance attract people all over the world. It is also an umbrella species of wildlife conservation; protecting the giant panda also protects other endangered wildlife sympatric with pandas.

  Jun 26, 2018
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  Hematopoietic hierarchy – an updated roadmap

  Hematopoiesis, a dynamic and well-organized process, is maintained by a rare number of multipotent cells – hematopoietic stem cells (HSCs). HSCs not only can self-renew to sustain the stability of HSC pool, but also can differentiate into different types of mature blood cells.

  Jun 22, 2018
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  Human Embryonic Stem Cells-derived Dopaminergic Neurons Alleviate Symptoms of Parkinson’s Disease in Monkeys

  Parkinson’s disease (PD) is one of the leading neural degenerative disorders, which is primarily caused by death of dopaminergic neurons in substantia nigra. This type of disorder is now possibly treated using stem cell-based strategy, such as transplantation of human embryonic stem cells (hESCs) differentiated derivatives.

  Jun 13, 2018
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  mTOR masters monocyte/macrophage development

  Monocyte/macrophage plays a critical role in innate immunity against invading pathogens and tissue repair during the period of inflammation resolution.

  Feb 26, 2018
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  Scientists Reveal Divergent and Parallel Routes in Convergence of High-altitude Passerine Birds

  Adaptive evolution in high-altitude vertebrates has been focused by scientists from medicine to evolutionary biologists for a century. Because of a different cardiorespiratory system and physiological regulation, the molecular mechanisms under adaptation in high-altitude environment evolved distinctively in birds from that in mammals.

  Feb 06, 2018
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  Panda tongues evolved to protect them from toxins, study suggests

  With their sharp canine teeth and a gut built to break down meat, pandas have kept many features of their carnivorous ancestors. But these bamboo-munching vegetarians sport one piece of anatomy that may be evolving at a more rapid clip: their tongue. As ancient pandas switched to a plant-based diet, their bitter taste perception got better, according to a new study, helping them detect the dangerous toxins in bamboo.

  Feb 01, 2018
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  Two new snout moth genera and three new species discovered in southern China

  New members have joined the ranks of the snout moths -- one of the largest groups within the insect order known formally as Lepidoptera, comprising all moths and butterflies.

  Jan 29, 2018
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  Novel Body Structure Likely Tied to Mating in New Extinct Insect Species

  Insects, widely distributed worldwide, are the most diverse group of animals on earth (more than one million species) and account for more than 50% of all living species (including bacteria, fungi, and viruses). Insects are divided into more than 30 insect orders, such as Coleoptera, Lepidoptera, Hymenoptera, etc.

  Jan 24, 2018
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  Endothelial-specific m6A modulates mouse hematopoietic stem and progenitor cell development via Notch signaling

  Hematopoietic stem cells (HSCs) can give rise to all blood lineages, including erythrocyte, myelocyte and lymphocyte, and maintain lifelong hematopoiesis in vertebrates. However, the limited source of matched donor-derived HSCs has greatly hindered their application in treatment of malignant blood diseases, therefore how to induce and expand HSCs in vitro has become one of the most desired approaches in clinic.However, to fulfill this end, a complete understanding of molecular mechanisms of HSC development in vivo is a prerequisite in this field.

  Nov 20, 2017